Citral is a naturally occurring scent ingredient; manufactured synthetically on a large scale; associated with allergies and contact dermatitis.
Function(s): Flavoring Agent; Fragrance Ingredient; MASKING
Other names: 2,6-Octadienal, 3,7-Dimethyl-; 2,6Octadienal, 3,7Dimethyl; 3,7-Dimethyl- 2,6-Octadienal; 3,7-Dimethyl-2,6-Octadienal; 3,7-Dimethyl-2,6-Octadienal; Lemsyn Gb; Nci-C56348
Developmental & reproductive toxicity: ○○○○○○○○○○○○
Allergies & immunotoxicity:
Natural or synthetic?
What Is It?
Citral is a component of lemongrass oil and the oils of verbena, lemon myrtle, lemon and orange. In cosmetics and personal care products, Citral is used in the formulation of many types of products including aftershave lotions, bath products, moisturizers, perfumes and colognes, skin care products and suntan products.
Why is it used in cosmetics and personal care products?
The Food and Drug Administration (FDA) includes Citral in its list of substances considered Generally Recognized As Safe (GRAS) as a synthetic flavoring substance. The safety of Citral has been evaluated by the Research Institute for Fragrance Materials Expert Panel (REXPAN). Based on this evaluation, an International Fragrance Association (IFRA) Standard has been established. The IFRA Standard restricts the use of Citral in fragrances because of potential sensitization.
Link to the IFRA Standards: http://www.ifraorg.org/en-us/standards_1
The Cosmetic Ingredient Review (CIR) defers review of individual fragrance ingredients to the IFRA program unless the ingredient has significant uses other than as a fragrance. In this case, the ingredient may be assessed by both the CIR Expert Panel and REXPAN.
More safety Information:
Link to FDA Code of Federal Regulations for Citral: http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr...
The Joint FAO/WHO Expert Committee on Food Additives (JECFA) established an Acceptable Daily Intake of up to 0.5 mg/kg body weight Citral when used as a flavoring agent.
Link to the JECFA safety evaluation of Citral: http://www.inchem.org/documents/jecfa/jeceval/jec_432.htm
The Flavor and Extract Manufacturers Association Expert Panel has reviewed the safety of Citral and determined that it is Generally Recognized as Safe (GRAS) for use as a flavoring substance. In Europe, Citral is included on the list of "allergenic" substances. The European Cosmetics Regulation requires manufacturers of cosmetics and personal care products to indicate the presence of certain "allergenic" substances in the list of ingredients if they are present above certain levels in the product (see Annex III). The presence of Citral must be indicated in the list of ingredients when its concentration exceeds: 0.001% in leave-on the skin products 0.01% in products that are rinsed off the skin.
Link to the EU Cosmetic Regulation: http://europa.eu/legislation_summaries/consumers/product_labelling_and_packaging/co0013_en.htm